分離済み変異体

tm3163

Allele Name

tm3163

Balance

Not Required

OutCross

Not Accepted

Sequence Name

Y55F3AM.12

Gene Name

dcap-1

Worm Base

Allele Name

tm3163

Gene Name

dcap-1

Sequence

Y55F3AM.12

Phenotype

homozygous viable. Dr. H. Zhang: normal locomotion, Gro and small brood size at 25 C.

Mutation site

74149/74150-74483/74484 (334 bp deletion)

Chromosome

Putative gene structure

complement(join(73580..73684, 74389..75073, 75140..75249, 75299..75397))

Map position

-22.41

Balancer

Map position of balancer

Sequence of primers

IntRev:AGCTAGCCGCGAAAAACCTC,ExtRev:ACCAGTATGAGCGACGCTAA,IntFwd:TACCTAAGCTAGACTAAGCC,ExtFwd:TAGGTGGGCGATTGCTGAGA

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Baiocchi T, Anesko K, Mercado N, Park H, Kin K, Strickhouser-Monzon B, Robles P, Bowman C, Wang H, Sternberg PW, Dillman AR.
Signaling by AWC Olfactory Neurons Is Necessary for Caenorhabditis elegans' Response to Prenol, an Odor Associated with Nematode-Infected Insects.
Genetics 2020 216(1) 145-157
[ PubMed ID = 32680884 ] [ RRC reference ]

Borbolis F, Rallis J, Kanatouris G, Kokla N, Karamalegkos A, Vasileiou C, Vakaloglou KM, Diallinas G, Stravopodis DJ, Zervas CG, Syntichaki P.
mRNA decapping is an evolutionarily conserved modulator of neuroendocrine signaling that controls development and ageing.
Elife 2020 9
[ PubMed ID = 32366357 ] [ RRC reference ]

Adachi T, Nagahama K, Izumi S.
The C. elegans mRNA decapping enzyme shapes morphology of cilia.
Biochem Biophys Res Commun 2017 493(1) 382-387
[ PubMed ID = 28887031 ] [ RRC reference ]

Borbolis F, Flessa CM, Roumelioti F, Diallinas G, Stravopodis DJ, Syntichaki P.
Neuronal function of the mRNA decapping complex determines survival of Caenorhabditis elegans at high temperature through temporal regulation of heterochronic gene expression.
Open Biol 2017 7(3)
[ PubMed ID = 28250105 ] [ RRC reference ]

Rousakis A, Vlanti A, Borbolis F, Roumelioti F, Kapetanou M, Syntichaki P.
Diverse functions of mRNA metabolism factors in stress defense and aging of Caenorhabditis elegans.
PLoS One 2014 9(7) e103365
[ PubMed ID = 25061667 ] [ RRC reference ]

Sun Y, Yang P, Zhang Y, Bao X, Li J, Hou W, Yao X, Han J, Zhang H.
A genome-wide RNAi screen identifies genes regulating the formation of P bodies in C. elegans and their functions in NMD and RNAi.
Protein Cell 2011 2(11) 918-39
[ PubMed ID = 22180091 ] [ RRC reference ]