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分離済み変異体

Allele Name		tm3136
Balance		Completed
OutCross		Not Accepted
Sequence Name		D2021.1
Gene Name		D2021.1
Worm Base	Allele Name	tm3136 (x1)
	Gene Name	D2021.1
	Sequence	D2021.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. R.H. Horvitz, Dr. A. Salcini: Mel, homozygous mothers lay lethal progeny (embryonic or L1). Dr. H. Sawa: 0% extra DTC. Dr. M. Han: early larval lethal.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		13919/13920-14155/14156 (236 bp deletion)
Chromosome		X
Putative gene structure		join(13888..13923, 13976..14052, 14106..14432, 14482..14602, 14935..15075, 15130..15402, 15519..15638, 15783..15915, 16607..16791, 16839..17159, 17492..18364, 18420..19009, 19058..19246, 19431..19551)
Map position		0.12
Balancer		,tmC24[tmIs1233 tm9718]
Map position of balancer
Sequence of primers		ExtFwd:CTCCGTTTCTAACGTTGATC,IntFwd:TGCATGAACACCGTATCGCT,ExtRev:GACTCATCACTGTCGTTGAC,IntRev:CATGCGTATTCTCGGTCTTT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Mazzetto M, Gonzalez LE, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis. Genome Res 2024 34(1) 57-69  [ PubMed ID = 38164610 ] [ RRC reference ] Vandamme J, Lettier G, Sidoli S, Di Schiavi E, Nørregaard Jensen O, Salcini AE. The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity. PLoS Genet 2012 8(5) e1002647  [ PubMed ID = 22570628 ] [ RRC reference ]