分離済み変異体

tm3120

Allele Nametm3120
BalanceNot Required
OutCrossNot Accepted
Sequence NameZK863.3
Gene Nameelpc-3
Worm BaseAllele Name tm3120
Gene Name elpc-3
Sequence ZK863.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. A. Bystrom: PLoS Genetics 5, e1000561 (2009)
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 13593/13594-13948/13949 (355 bp deletion)
ChromosomeV
Putative gene structurecomplement(join(12657..12914, 12957..13225, 13274..13910, 13960..14319, 14364..14504))
Map position3.72
Balancer
Map position of balancer
Sequence of primersExtRev:GGGTTCACAAAGAGCACTAC,IntRev:TCGTATGTGGTTAGGCGGTA,ExtFwd:CTCCACTAATCGCGCCGAAG,IntFwd:GCGCCGAAGGGATTAATATG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Eck RJ, Stair JG, Kraemer BC, Liachko NF.
Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Front Neurosci 2023 17 1300705 
[ PubMed ID = 38239833 ] [ RRC reference ]

Fernandes De Abreu DA, Salinas-Giegé T, Drouard L, Remy JJ.
Alanine tRNAs Translate Environment Into Behavior in Caenorhabditis elegans.
Front Cell Dev Biol 2020 8 571359 
[ PubMed ID = 33195203 ] [ RRC reference ]

Solinger JA, Paolinelli R, Klöss H, Scorza FB, Marchesi S, Sauder U, Mitsushima D, Capuani F, Stürzenbaum SR, Cassata G.
The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation.
PLoS Genet 2010 6(1) e1000820 
[ PubMed ID = 20107598 ] [ RRC reference ]

Chen C, Tuck S, Byström AS.
Defects in tRNA modification associated with neurological and developmental dysfunctions in Caenorhabditis elegans elongator mutants.
PLoS Genet 2009 5(7) e1000561 
[ PubMed ID = 19593383 ] [ RRC reference ]