分離済み変異体

tm3079

Allele Nametm3079
BalanceNot Required
OutCrossNot Accepted
Sequence NameT13B5.8
Gene Namesut-1
Worm BaseAllele Name tm3079
Gene Name sut-1
Sequence T13B5.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 30739/30740-31179/31180 (440 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(29240..29350, 29750..29967, 30830..31028, 31126..31210, 31261..31334, 31395..31415))
Map position-15.58
Balancer
Map position of balancer
Sequence of primersExtFwd:CTAGTGTGAATTGTAGCGGA,ExtRev:CGGGAGCCTCGAAAAAAGTG,IntFwd:GCGCTCCAATGCAAATATCG,IntRev:TCCAGGTATCAGAGGAAGAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Eijlers P, Al-Khafaji M, Soto-Martin E, Fasimoye R, Stead D, Wenzel M, Müller B, Pettitt J.
A nematode-specific ribonucleoprotein complex mediates interactions between the major nematode spliced leader snRNP and its target pre-mRNAs.
Nucleic Acids Res 2024 52(12) 7245-7260 
[ PubMed ID = 38676950 ] [ RRC reference ]

Philippe L, Pandarakalam GC, Fasimoye R, Harrison N, Connolly B, Pettitt J, Müller B.
An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly.
Nucleic Acids Res 2017 45(14) 8474-8483 
[ PubMed ID = 28582530 ] [ RRC reference ]