分離済み変異体

tm3075

Allele Nametm3075
BalanceNot Required
OutCrossNot Accepted
Sequence NameZK370.5
Gene Namepdhk-2
Worm BaseAllele Name tm3075
Gene Name pdhk-2
Sequence ZK370.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. K. Ashrafi: no L1 starvation phenotype.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 20686/20687-21044/21045 (358 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(19681..19929, 20211..20318, 20712..20810, 21076..21211, 22052..22155, 22206..22392, 22501..22755, 22983..23050))
Map position-0.07
Balancer
Map position of balancer
Sequence of primersExtFwd:GTGTTCCATCACGTGGCGGT,IntFwd:GGATACACCTCCTCCACGAT,ExtRev:TCTCTACCACCACTGCCCAT,IntRev:CTTCCGTGCAGGGAGTGTTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Kim S, Shin EJ, Hahm JH, Park PJ, Hwang JE, Paik YK.
PDHK-2 deficiency is associated with attenuation of lipase-mediated fat consumption for the increased survival of Caenorhabditis elegans dauers.
PLoS One 2012 7(7) e41755 
[ PubMed ID = 22848591 ] [ RRC reference ]