Home > 分離済み変異体 > tm3067

分離済み変異体

Allele Name		tm3067
Balance		Not Required
OutCross		Not Accepted
Sequence Name		C05C8.9b
Gene Name		hyls-1
Worm Base	Allele Name	tm3067
	Gene Name	hyls-1
	Sequence	C05C8.9b
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. K. Oegema: Genes & Dev. 23, 2046 (2009). Dr. O. Blacque: partially Dyf.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		13498/13499-13991/13992 (493 bp deletion)
Chromosome		V
Putative gene structure		join(13542..13638, 13694..13864, 13915..14135)
Map position		0.63
Balancer
Map position of balancer
Sequence of primers		ExtFwd:ACCCCACCATCTTGTGACTG,IntFwd:GTTACGGGTAGTTTAACGTG,ExtRev:AACGTTCTTCCATCGCTACT,IntRev:CATCGCTACTACACAGTCAC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Brinzer RA, Winter AD, Page AP. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. G3 (Bethesda) 2024 14(3)   [ PubMed ID = 38227795 ] [ RRC reference ] Yan H, Chen C, Chen H, Hong H, Huang Y, Ling K, Hu J, Wei Q. TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating. Nat Commun 2020 11(1) 2196  [ PubMed ID = 32366837 ] [ RRC reference ] Kazatskaya A, Kuhns S, Lambacher NJ, Kennedy JE, Brear AG, McManus GJ, Sengupta P, Blacque OE. Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells. Genetics 2017 207(4) 1423-1440  [ PubMed ID = 29021280 ] [ RRC reference ] Serwas D, Su TY, Roessler M, Wang S, Dammermann A. Centrioles initiate cilia assembly but are dispensable for maturation and maintenance in C. elegans. J Cell Biol 2017 216(6) 1659-1671  [ PubMed ID = 28411189 ] [ RRC reference ] Wei Q, Zhang Y, Schouteden C, Zhang Y, Zhang Q, Dong J, Wonesch V, Ling K, Dammermann A, Hu J. The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gate. Nat Commun 2016 7 12437  [ PubMed ID = 27534274 ] [ RRC reference ] Dammermann A, Pemble H, Mitchell BJ, McLeod I, Yates JR 3rd, Kintner C, Desai AB, Oegema K. The hydrolethalus syndrome protein HYLS-1 links core centriole structure to cilia formation. Genes Dev 2009 23(17) 2046-59  [ PubMed ID = 19656802 ] [ RRC reference ]