Home > 分離済み変異体 > tm3041

分離済み変異体

Allele Name		tm3041
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F55F8.6
Gene Name		F55F8.6
Worm Base	Allele Name	tm3041
	Gene Name	F55F8.6
	Sequence	F55F8.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		12966/12967-T-13426/13427 (460 bp deletion + 1 bp insertion)
Chromosome		I
Putative gene structure		complement(join(13063..13272, 13321..13596))
Map position		0.3
Balancer
Map position of balancer
Sequence of primers		IntRev:CGTTCCGGAGCACATCACAG,ExtRev:CCTAGGAACCGACAAGCGAA,IntFwd:GTATGAAGGGGACTAACGAA,ExtFwd:ACCGTATGAAGGGGACTAAC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Traa A, Tamez González AA, Van Raamsdonk JM. Developmental disruption of the mitochondrial fission gene drp-1 extends the longevity of daf-2 insulin/IGF-1 receptor mutant. Geroscience 2025 47(1) 877-902  [ PubMed ID = 39028454 ] [ RRC reference ] Machiela E, Liontis T, Dues DJ, Rudich PD, Traa A, Wyman L, Kaufman C, Cooper JF, Lew L, Nadarajan S, Senchuk MM, Van Raamsdonk JM. Disruption of mitochondrial dynamics increases stress resistance through activation of multiple stress response pathways. FASEB J 2020 34(6) 8475-8492  [ PubMed ID = 32385951 ] [ RRC reference ] Oh KH, Sheoran S, Richmond JE, Kim H. Alcohol induces mitochondrial fragmentation and stress responses to maintain normal muscle function in Caenorhabditis elegans. FASEB J 2020 34(6) 8204-8216  [ PubMed ID = 32294300 ] [ RRC reference ] Shen Q, Yamano K, Head BP, Kawajiri S, Cheung JT, Wang C, Cho JH, Hattori N, Youle RJ, van der Bliek AM. Mutations in Fis1 disrupt orderly disposal of defective mitochondria. Mol Biol Cell 2014 25(1) 145-59  [ PubMed ID = 24196833 ] [ RRC reference ]