分離済み変異体

tm3040

Allele Nametm3040
BalanceNot Required
OutCrossNot Accepted
Sequence NameY54G2A.25
Gene Namelad-2
Worm BaseAllele Name tm3040
Gene Name lad-2
Sequence Y54G2A.25
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. L. Chen: J. Cell Biol. 180, 233 (2008).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 224118/224119-224445/224446 (327 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(214208..214285, 215029..215279, 215955..216146, 216197..216352, 216563..216691, 216996..217107, 217364..217554, 217604..217727, 217772..218140, 218590..218723, 218771..218889, 218945..219104, 219519..219639, 223240..223400, 223454..223741, 224310..224594, 224645..224847, 226089..226209, 226993..227063, 227110..227226, 227951..228065, 228111..228177))
Map position-6.72
Balancer
Map position of balancer
Sequence of primersIntFwd:GCTAGCATTGCATTGGTAGA,IntRev:AACTATCCGGAGCCGACACA,ExtFwd:ATCCCAACGGATTGCTAGCA,ExtRev:CCTAGACGATTCCTCCGTAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Wang X, Zhang W, Cheever T, Schwarz V, Opperman K, Hutter H, Koepp D, Chen L.
The C. elegans L1CAM homologue LAD-2 functions as a coreceptor in MAB-20/Sema2 mediated axon guidance.
J Cell Biol 2008 180(1) 233-46 
[ PubMed ID = 18195110 ] [ RRC reference ]