分離済み変異体

tm2991

Allele Nametm2991
BalanceNot Required
OutCrossNot Accepted
Sequence NameD1037.4
Gene Namerab-8
Worm BaseAllele Name tm2991
Gene Name rab-8
Sequence D1037.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 22495/22496-AA-22809/22810 (314 bp deletion + 2 bp insertion)
ChromosomeI
Putative gene structurecomplement(join(22559..22948, 23008..23068, 23116..23270, 23318..23347))
Map position-2.95
Balancer
Map position of balancer
Sequence of primersExtFwd:CGCTGGTATATGAATCTGAC,IntFwd:CTCATCAGAATGCTGGGTGT,ExtRev:CTGATCGCATCCGGCTAGTT,IntRev:CGGGGTAATTCCCTCGCCAT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Martínez-Velázquez LA, Ringstad N.
Antagonistic regulation of trafficking to Caenorhabditis elegans sensory cilia by a Retinal Degeneration 3 homolog and retromer.
Proc Natl Acad Sci U S A 2018 115(3) E438-E447 
[ PubMed ID = 29282322 ] [ RRC reference ]

Sasidharan N, Sumakovic M, Hannemann M, Hegermann J, Liewald JF, Olendrowitz C, Koenig S, Grant BD, Rizzoli SO, Gottschalk A, Eimer S.
RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2012 109(46) 18944-9 
[ PubMed ID = 23100538 ] [ RRC reference ]