Home > 分離済み変異体 > tm2990

分離済み変異体

Allele Name		tm2990
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F18E9.2
Gene Name		nlp-7
Worm Base	Allele Name	tm2990
	Gene Name	nlp-7
	Sequence	F18E9.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. Y. Iino: normal chemotaxis to NaCl, normal salt chemotaxis learning. Dr. Z-X. Wu: normal chemotaxis against glycerol, Cu and normal nose touch response.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		29985/29986-30220/30221 (235 bp deletion)
Chromosome		X
Putative gene structure		join(29870..29937, 30086..30118, 30169..30288, 30342..30486)
Map position		0.15
Balancer
Map position of balancer
Sequence of primers		ExtFwd:GACCTGATATGTGCTGAGAT,IntFwd:CTCTGTTTAGCCTATCACCA,ExtRev:GCTAGTGAAGGGAGGATCAT,IntRev:CAAGTACTAGTACCTCGGGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Xue W, Chen Y, Lei Z, Wang Y, Liu J, Wen X, Xu F, Chen P, Wu Z, Jin YN, Yu YV. Calcium levels in ASER neurons determine behavioral valence by engaging distinct neuronal circuits in C. elegans. Nat Commun 2025 16(1) 1814  [ PubMed ID = 39979341 ] [ RRC reference ] Staum M, Abraham AC, Arbid R, Birari VS, Dominitz M, Rabinowitch I. Behavioral adjustment of C. elegans to mechanosensory loss requires intact mechanosensory neurons. PLoS Biol 2024 22(7) e3002729  [ PubMed ID = 39024405 ] [ RRC reference ] Liu H, Wu JJ, Li R, Wang PZ, Huang JH, Xu Y, Zhao JL, Wu PP, Li SJ, Wu ZX. Disexcitation in the ASH/RIM/ADL negative feedback circuit fine-tunes hyperosmotic sensation and avoidance in Caenorhabditis elegans. Front Mol Neurosci 2023 16 1101628  [ PubMed ID = 37008778 ] [ RRC reference ] Park SK, Link CD, Johnson TE. Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans. FASEB J 2010 24(2) 383-92  [ PubMed ID = 19783783 ] [ RRC reference ] Takayama J, Faumont S, Kunitomo H, Lockery SR, Iino Y. Single-cell transcriptional analysis of taste sensory neuron pair in Caenorhabditis elegans. Nucleic Acids Res 2010 38(1) 131-42  [ PubMed ID = 19875417 ] [ RRC reference ]