Home > 分離済み変異体 > tm2979

分離済み変異体

Allele Name		tm2979
Balance		Not Required
OutCross		Not Accepted
Sequence Name		Y39B6A.2
Gene Name		pph-5
Worm Base	Allele Name	tm2979
	Gene Name	pph-5
	Sequence	Y39B6A.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		232709/232710-232874/232875 (165 bp deletion)
Chromosome		V
Putative gene structure		join(232499..232622, 232681..232928, 233560..233739, 234409..234651, 235481..235729, 237179..237288, 238843..239095, 240784..240867)
Map position		20.21
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CTCCGAAATGGCTGCCACTA,IntRev:CACCTTAACAACCGCCTGAT,ExtRev:AAGCTGTCAGCAGCGCCCAA,IntFwd:GGCTGCCACTATAACAGATG
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Mazzetto M, Gonzalez LE, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis. Genome Res 2024 34(1) 57-69  [ PubMed ID = 38164610 ] [ RRC reference ] Fielder SM, Rosenfeld JA, Burrage LC, Emrick L, Lalani S, Attali R, Bembenek JN, Hoang H, Baldridge D, Silverman GA, Undiagnosed Diseases Network, Schedl T, Pak SC. Functional analysis of a novel de novo variant in PPP5C associated with microcephaly, seizures, and developmental delay. Mol Genet Metab 2022 136(1) 65-73  [ PubMed ID = 35361529 ] [ RRC reference ] Melesse M, Sloan DE, Benthal JT, Caylor Q, Gosine K, Bai X, Bembenek JN. Genetic Identification of Separase Regulators in Caenorhabditis elegans. G3 (Bethesda) 2018 8(2) 695-705  [ PubMed ID = 29246899 ] [ RRC reference ] Richie CT, Bembenek JN, Chestnut B, Furuta T, Schumacher JM, Wallenfang M, Golden A. Protein phosphatase 5 is a negative regulator of separase function during cortical granule exocytosis in C. elegans. J Cell Sci 2011 124(Pt 17) 2903-13  [ PubMed ID = 21878498 ] [ RRC reference ]