分離済み変異体

tm2974

Allele Nametm2974
BalanceNot Required
OutCrossNot Accepted
Sequence NameW05B5.2
Gene NameW05B5.2
Worm BaseAllele Name tm2974
Gene Name W05B5.2
Sequence W05B5.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 24049/24050-24355/24356 (306 bp deletion)
ChromosomeI
Putative gene structurejoin(20852..20994, 21666..21813, 23781..23927, 23980..24094, 24139..24233, 24435..24589, 24845..24955, 25420..25654)
Map position17.18
Balancer
Map position of balancer
Sequence of primersExtRev:ACATAGCATCCGGACCGCTT,IntRev:TCGTATGCTGATTTGTCGGT,ExtFwd:AACGGAGAAACACGATGGTC,IntFwd:CAGCGCAACGCTCTCAACTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Otarigho B, Butts AF, Aballay A.
Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans.
Elife 2024 12  
[ PubMed ID = 38446031 ] [ RRC reference ]

Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R.
Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans.
J Neurosci 2013 33(35) 14107-16 
[ PubMed ID = 23986246 ] [ RRC reference ]

Mills H, Wragg R, Hapiak V, Castelletto M, Zahratka J, Harris G, Summers P, Korchnak A, Law W, Bamber B, Komuniecki R.
Monoamines and neuropeptides interact to inhibit aversive behaviour in Caenorhabditis elegans.
EMBO J 2012 31(3) 667-78 
[ PubMed ID = 22124329 ] [ RRC reference ]

Harris G, Mills H, Wragg R, Hapiak V, Castelletto M, Korchnak A, Komuniecki RW.
The monoaminergic modulation of sensory-mediated aversive responses in Caenorhabditis elegans requires glutamatergic/peptidergic cotransmission.
J Neurosci 2010 30(23) 7889-99 
[ PubMed ID = 20534837 ] [ RRC reference ]