分離済み変異体

tm2960

Allele Nametm2960
BalanceCompleted
OutCrossNot Accepted
Sequence NameR119.4
Gene Namepqn-59
Worm BaseAllele Name tm2960 (x1)
Gene Name pqn-59
Sequence R119.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. J. Schumacher: Sick but viable as homozygote.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 22962/22963-23382/23383 (420 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(22040..22924, 22979..23351, 23401..23717, 23767..24014, 24062..24266, 24587..24697))
Map position-19.08
Balancer,hT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersIntRev:GCACCGGTTTCGTCGATCGA,ExtRev:AGCCGGAAGAGGGCAGTTAT,IntFwd:GTACGGCTTATTCATGCCAT,ExtFwd:GGGGAGCAAAGTCGCTGACT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Carlston C, Weinmann R, Stec N, Abbatemarco S, Schwager F, Wang J, Ouyang H, Ewald CY, Gotta M, Hammell CM.
PQN-59 antagonizes microRNA-mediated repression during post-embryonic temporal patterning and modulates translation and stress granule formation in C. elegans.
PLoS Genet 2021 17(11) e1009599 
[ PubMed ID = 34807903 ] [ RRC reference ]