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分離済み変異体

Allele Name		tm2939
Balance		Completed
OutCross		Not Accepted
Sequence Name		D2085.6
Gene Name		piga-1
Worm Base	Allele Name	tm2939 (x1)
	Gene Name	piga-1
	Sequence	D2085.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		20425/20426-20749/20750 (324 bp deletion)
Chromosome		II
Putative gene structure		complement(join(19430..19586, 19636..19819, 19879..20194, 20246..20611, 20728..20850, 20899..21055, 21112..21143))
Map position		0.83
Balancer		mIn1,mIn1 [e128 mIs14]
Map position of balancer
Sequence of primers		IntRev:GTCCGTACAGTATTGCGTAA,ExtRev:GGGCGTCATTGCATCTGCAA,ExtFwd:TATGGGGGAGCATTCCGAGA,IntFwd:GACCATCTCCGCCAATTATG
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Ihara S, Nakayama S, Murakami Y, Suzuki E, Asakawa M, Kinoshita T, Sawa H. PIGN prevents protein aggregation in the endoplasmic reticulum independently of its function in the GPI synthesis. J Cell Sci 2017 130(3) 602-613  [ PubMed ID = 27980068 ] [ RRC reference ] Budirahardja Y, Doan TD, Zaidel-Bar R. Glycosyl phosphatidylinositol anchor biosynthesis is essential for maintaining epithelial integrity during Caenorhabditis elegans embryogenesis. PLoS Genet 2015 11(3) e1005082  [ PubMed ID = 25807459 ] [ RRC reference ] Murata D, Nomura KH, Dejima K, Mizuguchi S, Kawasaki N, Matsuishi-Nakajima Y, Ito S, Gengyo-Ando K, Kage-Nakadai E, Mitani S, Nomura K. GPI-anchor synthesis is indispensable for the germline development of the nematode Caenorhabditis elegans. Mol Biol Cell 2012 23(6) 982-95  [ PubMed ID = 22298425 ] [ RRC reference ]