分離済み変異体

tm2915

Allele Nametm2915
BalanceNot Required
OutCrossNot Accepted
Sequence NameC05C10.6
Gene Nameufd-3
Worm BaseAllele Name tm2915
Gene Name ufd-3
Sequence C05C10.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 25347/25348-26094/26095 (747 bp deletion)
ChromosomeII
Putative gene structurejoin(24368..24412, 24458..24770, 24820..24926, 24980..25735, 25786..26101, 26156..26263, Z66515.1:102..235, Z66515.1:292..644, Z66515.1:699..924, Z66515.1:971..1075, Z66515.1:1123..1236)
Map position1.8
Balancer
Map position of balancer
Sequence of primersExtFwd:TGGCAGATGACGGTCTCGGT,IntRev:AGGTACGTATCTTCCGGATC,IntFwd:TCTCGGTGACGTGCCAATGG,ExtRev:CCAGTGTCAAAGCCACTCGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Yeon J, Porwal C, McGrath PT, Sengupta P.
Identification of a spontaneously arising variant affecting thermotaxis behavior in a recombinant inbred Caenorhabditis elegans line.
G3 (Bethesda) 2023 13(10)  
[ PubMed ID = 37572357 ] [ RRC reference ]

Jablonski AM, Lamitina T, Liachko NF, Sabatella M, Lu J, Zhang L, Ostrow LW, Gupta P, Wu CY, Doshi S, Mojsilovic-Petrovic J, Lans H, Wang J, Kraemer B, Kalb RG.
Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance.
J Neurosci 2015 35(42) 14286-306 
[ PubMed ID = 26490867 ] [ RRC reference ]

Murayama Y, Ogura T, Yamanaka K.
Characterization of C-terminal adaptors, UFD-2 and UFD-3, of CDC-48 on the polyglutamine aggregation in C. elegans.
Biochem Biophys Res Commun 2015 459(1) 154-60 
[ PubMed ID = 25721663 ] [ RRC reference ]

Segref A, Torres S, Hoppe T.
A screenable in vivo assay to study proteostasis networks in Caenorhabditis elegans.
Genetics 2011 187(4) 1235-40 
[ PubMed ID = 21288877 ] [ RRC reference ]