分離済み変異体

tm2910

Allele Nametm2910
BalanceCompleted
OutCrossNot Accepted
Sequence NameR02D3.2
Gene Namecogc-8
Worm BaseAllele Name tm2910
Gene Name cogc-8
Sequence R02D3.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 16454/16455-A-17217/17218 (763 bp deletion + 1 bp insertion)
ChromosomeIV
Putative gene structurejoin(15576..15639, 15686..15810, 15861..16031, 16083..16193, 16243..16446, 16500..16610, 16694..16812, 16941..17496, 18121..18891)
Map position-26.65
Balancerdpy-9 (e12) IV
Map position of balancer
Sequence of primersExtFwd:TACGGGCAGCCAACGCGATT,IntFwd:TATCGCCGATTTGCCTTTAC,ExtRev:CCGCTTAGAAATCGAGGATC,IntRev:CTAACAGTTGCCGGCGGGAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Kong X, Ning C, Liang Z, Yang C, Wu Y, Li Y, Wu A, Wang Y, Wang S, Fan H, Xiao W, Wu J, Sun Z, Yuan Z.
Koumine inhibits IL-1β-induced chondrocyte inflammation and ameliorates extracellular matrix degradation in osteoarthritic cartilage through activation of PINK1/Parkin-mediated mitochondrial autophagy.
Biomed Pharmacother 2024 173 116273 
[ PubMed ID = 38412715 ] [ RRC reference ]

Yamamoto TG, Watanabe S, Essex A, Kitagawa R.
SPDL-1 functions as a kinetochore receptor for MDF-1 in Caenorhabditis elegans.
J Cell Biol 2008 183(2) 187-94 
[ PubMed ID = 18936247 ] [ RRC reference ]

Tarailo M, Tarailo S, Rose AM.
Synthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components.
Genetics 2007 177(4) 2525-30 
[ PubMed ID = 18073444 ] [ RRC reference ]