分離済み変異体

tm2909

Allele Nametm2909
Allele Type通常株
Sequence NameF25D7.1
Gene Namecup-2
Worm BaseAllele Name tm2909
Gene Name cup-2
Sequence F25D7.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8524/8525-8845/8846 (321 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(8386..8796, 9023..9199, 9257..9406))
Map position4.99
Balancer
Map position of balancer
Sequence of primersIntRev:GGTACACGCGTATGTATTTC,ExtRev:AGCGTTTTCACTGCGTCAAG,IntFwd:TAGGGGCAAGGCAATACAAG,ExtFwd:TTCTGGCTGTCGCATCCACT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Cheung TP, Choe JY, Richmond JE, Kim H.
BK channel density is regulated by endoplasmic reticulum associated degradation and influenced by the SKN-1A/NRF1 transcription factor.
PLoS Genet 2020 16(6) e1008829 
[ PubMed ID = 32502151 ] [ RRC reference ]

Jablonski AM, Lamitina T, Liachko NF, Sabatella M, Lu J, Zhang L, Ostrow LW, Gupta P, Wu CY, Doshi S, Mojsilovic-Petrovic J, Lans H, Wang J, Kraemer B, Kalb RG.
Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance.
J Neurosci 2015 35(42) 14286-306 
[ PubMed ID = 26490867 ] [ RRC reference ]