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分離済み変異体

Allele Name		tm289
Balance		Completed
OutCross		Not Accepted
Sequence Name		F22D3.6 + F22D3.1
Gene Name		malt-1 + ceh-38
Worm Base	Allele Name	tm289 (x1)
	Gene Name	malt-1 + ceh-38
	Sequence	F22D3.6 + F22D3.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. Y-C. Wu: Let caused metabolic defects.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		25882/25883-AAAAAATTTTATG-26855/26856 (973 bp deletion)
Chromosome		II
Putative gene structure		F22D3.6 = complement(join(22981..23313, 23359..23447, 23739..23888, 23962..24058, 24106..24220, 24428..24501, 24550..24662, 24711..24810, 25106..25329, 25379..25539, 25582..25750, 25911..26001, 26049..26130, 26184..26305)); F22D3.1 = join(26644..26708, 27008..27111, 27157..27468, 27526..27619, 27748..28063, 28213..28672, 28793..29033, 29167..29253, 29383..30412, 26644..26708, 27008..27111, 27157..27468, 27526..27619, 27748..28063, 28186..28672, 28793..29033, 29167..29253, 29383..30412)
Map position		0.15
Balancer		,mnC1 [dpy-10(e128) unc52(e444) nIs190 let-?]
Map position of balancer
Sequence of primers		ExtFwd:TCCGAATATGGTGAGCCTTC,IntFwd:TTGATGTTCATTCGAGCATTT,ExtRev:TTGCTAATGGCTGTGCAACC,IntRev:TTCGACGGAATGTCTCACGT
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Cao W, Fan Q, Amparado G, Begic D, Godini R, Gopal S, Pocock R. A nucleic acid binding protein map of germline regulation in Caenorhabditis elegans. Nat Commun 2024 15(1) 6884  [ PubMed ID = 39128930 ] [ RRC reference ] Vérièpe-Salerno J, Podavini S, Long MJC, Kolotuev I, Cuendet M, Thome M. MALT-1 shortens lifespan by inhibiting autophagy in the intestine of C. elegans. Autophagy Rep 2023 2(1) 2277584  [ PubMed ID = 38510643 ] [ RRC reference ] Staal J, Driege Y, Haegman M, Borghi A, Hulpiau P, Lievens L, Gul IS, Sundararaman S, Gonçalves A, Dhondt I, Pinzón JH, Braeckman BP, Technau U, Saeys Y, van Roy F, Beyaert R. Ancient Origin of the CARD-Coiled Coil/Bcl10/MALT1-Like Paracaspase Signaling Complex Indicates Unknown Critical Functions. Front Immunol 2018 9 1136  [ PubMed ID = 29881386 ] [ RRC reference ]