分離済み変異体

tm2884

Allele Nametm2884
BalanceCompleted
OutCrossNot Accepted
Sequence NameH25P06.2a
Gene Namecdk-9
Worm BaseAllele Name tm2884 (x1)
Gene Name cdk-9
Sequence H25P06.2a
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 20129/20130-20318/20319 (189 bp deletion)
ChromosomeI
Putative gene structurejoin(17793..17842, 19133..19180, 20008..20232, 20954..21126, Z83118.1:615..890, Z83118.1:1813..2036, Z83118.1:3851..3991, Z83118.1:4076..4117, Z83118.1:4666..4857)
Map position6.74
BalancerhT2
Map position of balancer
Sequence of primersExtFwd:TCAGAGCTCTAATCGGCGGT,IntFwd:TAATCGGCGGTCAAACGACT,IntRev:GGCCGAGGTATACCTAGTGG,ExtRev:TTGCGGTGGCCGAGGTATAC
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Knittel TL, Montgomery BE, Reed KJ, Chong MC, Isolehto IJ, Cafferty ER, Smith MJ, Sprister RA, Magelky CN, Scherman H, Ketting RF, Montgomery TA.
Interdependence of Pasha and Drosha for localization and function of the Microprocessor in C. elegans.
Nat Commun 2025 16(1) 5595 
[ PubMed ID = 40595566 ] [ RRC reference ]

Montgomery BE, Knittel TL, Reed KJ, Chong MC, Isolehto IJ, Cafferty ER, Smith MJ, Sprister RA, Magelky CN, Scherman H, Ketting RF, Montgomery TA.
Regulation of Microprocessor assembly and localization via Pasha's WW domain in C. elegans.
bioRxiv 2024   
[ PubMed ID = 38712061 ] [ RRC reference ]

Bowman EA, Bowman CR, Ahn JH, Kelly WG.
Phosphorylation of RNA polymerase II is independent of P-TEFb in the C. elegans germline.
Development 2013 140(17) 3703-13 
[ PubMed ID = 23903194 ] [ RRC reference ]