分離済み変異体

tm2873

Allele Nametm2873
BalanceCompleted
OutCrossNot Accepted
Sequence NameC56C10.8
Gene Nameicd-1
Worm BaseAllele Name tm2873 (x1)
Gene Name icd-1
Sequence C56C10.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. K. Subramaniam: normal locomotion. Dr. H. Sawa: arrest at L2-L3, weak Psa.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 14247/14248-14490/14491 (243 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(13681..13739, 13789..13917, 13967..14075, 14122..14235, 14280..14354))
Map position-0.12
BalancermIn1 [e128 mIs14]
Map position of balancer
Sequence of primersIntFwd:CATCGGCTTTCGTCTCGTTC,ExtFwd:CTATCCGTACCGTTCATCTC,IntRev:TCCGTGCCTGAATTTAGGCT,ExtRev:GGAATGTTCGGGTCTCGCGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Guo B, Huang J, Wu W, Feng D, Wang X, Chen Y, Zhang H.
The nascent polypeptide-associated complex is essential for autophagic flux.
Autophagy 2014 10(10) 1738-48 
[ PubMed ID = 25126725 ] [ RRC reference ]

Huang CY, Chen JY, Wu SC, Tan CH, Tzeng RY, Lu PJ, Wu YF, Chen RH, Wu YC.
C. elegans EIF-3.K promotes programmed cell death through CED-3 caspase.
PLoS One 2012 7(5) e36584 
[ PubMed ID = 22590572 ] [ RRC reference ]