分離済み変異体

tm2858

Allele Nametm2858
BalanceNot Required
OutCrossNot Accepted
Sequence NameY73B6BL.7
Gene Namecsp-2
Worm BaseAllele Name tm2858
Gene Name csp-2
Sequence Y73B6BL.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 28967/28968-29201/29202 (234 bp deletion)
ChromosomeIV
Putative gene structurejoin(21611..21668, 21717..21761, 23028..23173, 23521..23670, 23772..23958, 24486..25184, 25323..25400, 25454..25522, 25838..25948, 26210..26320, 28295..28545, 28591..28792, 28840..28934, 28979..29215, 29258..29299)
Map position3.15
Balancer
Map position of balancer
Sequence of primersExtFwd:GCCGGGCTATCATAATTAAC,ExtRev:ATACTGATCACCGAGGCCAT,IntFwd:ACGTTTGGGATATCAGTCGA,IntRev:CACGTCATTTCTAGACGTCG
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Jeong PY, Kumar A, Joshi PM, Rothman JH.
Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death.
Sci Rep 2020 10(1) 6159 
[ PubMed ID = 32273538 ] [ RRC reference ]

Geng X, Zhou QH, Kage-Nakadai E, Shi Y, Yan N, Mitani S, Xue D.
Caenorhabditis elegans caspase homolog CSP-2 inhibits CED-3 autoactivation and apoptosis in germ cells.
Cell Death Differ 2009 16(10) 1385-94 
[ PubMed ID = 19575016 ] [ RRC reference ]