Home > 分離済み変異体 > tm2841

分離済み変異体

Allele Name		tm2841
Balance		Completed
OutCross		Not Accepted
Sequence Name		C06G3.2
Gene Name		klp-18
Worm Base	Allele Name	tm2841 (x1)
	Gene Name	klp-18
	Sequence	C06G3.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. H. Sawa: not Psa., Dr. I. Mori: maternal effect embryonic lethal, weakly thermotaxis abnormal when raised at 20˚C, but normal thermotaxis when raised at 17˚C and 23˚C.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		28622/28623-29106/29107 (484 bp deletion)
Chromosome		IV
Putative gene structure		join(28272..28522, 28569..29658, 29706..30070, 30122..30309, 30359..30693, 30743..31162, 31208..31357)
Map position		3.28
Balancer		nT1 [qIs51]
Map position of balancer
Sequence of primers		ExtFwd:TGGGACCGTGTTCGCCTATG,IntRev:TGACGTTGCCTCTTCGTGCT,IntFwd:ACAGGGTAAGTGCTTCCAAT,ExtRev:CCCTGAAGCAATCGTTCCGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Mazzetto M, Gonzalez LE, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis. Genome Res 2024 34(1) 57-69  [ PubMed ID = 38164610 ] [ RRC reference ] Mullen TJ, Wignall SM. Interplay between microtubule bundling and sorting factors ensures acentriolar spindle stability during C. elegans oocyte meiosis. PLoS Genet 2017 13(9) e1006986  [ PubMed ID = 28910277 ] [ RRC reference ] Wolff ID, Tran MV, Mullen TJ, Villeneuve AM, Wignall SM. Assembly of Caenorhabditis elegans acentrosomal spindles occurs without evident microtubule-organizing centers and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1. Mol Biol Cell 2016 27(20) 3122-3131  [ PubMed ID = 27559133 ] [ RRC reference ]