分離済み変異体

tm2815

Allele Nametm2815
BalanceCompleted
OutCrossNot Accepted
Sequence NameR06C7.8
Gene Namebub-1
Worm BaseAllele Name tm2815 (x1)
Gene Name bub-1
Sequence R06C7.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. H. Sawa: non Psa. Dr. L. Dreier: Ste, Unc, paralyzes faster in the presence of aldicarb.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 21101/21102-21505/21506 (404 bp deletion)
ChromosomeI
Putative gene structurejoin(19602..19675, 19721..20250, 20294..21205, 21250..21437, 21483..22252, 22297..22786)
Map position1.86
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersIntFwd:GTTATGGGTCGATCTAGTAC,ExtRev:TCTGGGGAGGACGCACAAGA,IntRev:CCATGGATTGATGTCTCCTT,ExtFwd:GAAGCGATGCTCCGTCTCTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Wang X, Liu M, Li W, Suh CD, Zhu Z, Jin Y, Fan Q.
The function of a spindle checkpoint gene bub-1 in C. elegans development.
PLoS One 2009 4(6) e5912 
[ PubMed ID = 19526056 ] [ RRC reference ]

Tarailo M, Tarailo S, Rose AM.
Synthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components.
Genetics 2007 177(4) 2525-30 
[ PubMed ID = 18073444 ] [ RRC reference ]