Home > 分離済み変異体 > tm2720

分離済み変異体

Allele Name		tm2720
Balance		Not Required
OutCross		Not Accepted
Sequence Name		B0024.9
Gene Name		trx-2
Worm Base	Allele Name	tm2720
	Gene Name	trx-2
	Sequence	B0024.9
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		28467/28468-28685/28686 (218 bp deletion)
Chromosome		V
Putative gene structure		join(28180..28254, 28302..28391, 28447..28641)
Map position		2.47
Balancer
Map position of balancer
Sequence of primers		IntRev:GCTATGCCAAAATGGCTGCA,IntFwd:GTCAAACCAACTCTGGCGAC,ExtRev:TCCGCTATGCCAAAATGGCT,ExtFwd:GCCATCTCCGTCAAACCAAC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Harris-Gauthier N, Traa A, AlOkda A, Moldakozhayev A, Anglas U, Soo SK, Van Raamsdonk JM. Mitochondrial thioredoxin system is required for enhanced stress resistance and extended longevity in long-lived mitochondrial mutants. Redox Biol 2022 53 102335  [ PubMed ID = 35598379 ] [ RRC reference ] McCallum KC, Liu B, Fierro-González JC, Swoboda P, Arur S, Miranda-Vizuete A, Garsin DA. TRX-1 Regulates SKN-1 Nuclear Localization Cell Non-autonomously in Caenorhabditis elegans. Genetics 2016 203(1) 387-402  [ PubMed ID = 26920757 ] [ RRC reference ] Cacho-Valadez B, Muñoz-Lobato F, Pedrajas JR, Cabello J, Fierro-González JC, Navas P, Swoboda P, Link CD, Miranda-Vizuete A. The characterization of the Caenorhabditis elegans mitochondrial thioredoxin system uncovers an unexpected protective role of thioredoxin reductase 2 in β-amyloid peptide toxicity. Antioxid Redox Signal 2012 16(12) 1384-400  [ PubMed ID = 22220943 ] [ RRC reference ]