分離済み変異体

tm2716

Allele Nametm2716
Allele Typeバランス済
Sequence NameF54E7.3
Gene Namepar-3
Worm BaseAllele Name tm2716
Gene Name par-3
Sequence F54E7.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 16460/16461-17061/17062 (601 bp deletion)
ChromosomeIII
Putative gene structurejoin(10689..10856, 11263..11352, 11406..11468, 15070..15177, 15256..15403, 15867..16850, 17048..18163, 18537..18683, 18788..19010, 19435..19696, 21037..21212, 21564..22218)
Map position-1.46
BalancerhT2 bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersExtFwd:TCAACCATCAGGCTCACCGT,IntFwd:CTCGAGACTTTGCGCCACAG,ExtRev:AGGGTCGTGGTCATCAACAC,IntRev:GTGCTGTGGATCAGCAGCTG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Achilleos A, Wehman AM, Nance J.
PAR-3 mediates the initial clustering and apical localization of junction and polarity proteins during C. elegans intestinal epithelial cell polarization.
Development 2010 137(11) 1833-42 
[ PubMed ID = 20431121 ] [ RRC reference ]

Feldman JL, Priess JR.
A role for the centrosome and PAR-3 in the hand-off of MTOC function during epithelial polarization.
Curr Biol 2012 22(7) 575-82 
[ PubMed ID = 22425160 ] [ RRC reference ]

Beatty A, Morton D, Kemphues K.
The C. elegans homolog of Drosophila Lethal giant larvae functions redundantly with PAR-2 to maintain polarity in the early embryo.
Development 2010 137(23) 3995-4004 
[ PubMed ID = 21041363 ] [ RRC reference ]