Home > 分離済み変異体 > tm2716

分離済み変異体

Allele Name		tm2716
Balance		Completed
OutCross		Not Accepted
Sequence Name		F54E7.3
Gene Name		par-3
Worm Base	Allele Name	tm2716 (x1)
	Gene Name	par-3
	Sequence	F54E7.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		16460/16461-17061/17062 (601 bp deletion)
Chromosome		III
Putative gene structure		join(10689..10856, 11263..11352, 11406..11468, 15070..15177, 15256..15403, 15867..16850, 17048..18163, 18537..18683, 18788..19010, 19435..19696, 21037..21212, 21564..22218)
Map position		-1.46
Balancer		hT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primers		ExtFwd:TCAACCATCAGGCTCACCGT,IntFwd:CTCGAGACTTTGCGCCACAG,ExtRev:AGGGTCGTGGTCATCAACAC,IntRev:GTGCTGTGGATCAGCAGCTG
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Rodrigues NTL, Bland T, Ng K, Hirani N, Goehring NW. Quantitative perturbation-phenotype maps reveal nonlinear responses underlying robustness of PAR-dependent asymmetric cell division. PLoS Biol 2024 22(12) e3002437  [ PubMed ID = 39652540 ] [ RRC reference ] Mazzetto M, Gonzalez LE, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis. Genome Res 2024 34(1) 57-69  [ PubMed ID = 38164610 ] [ RRC reference ] Feldman JL, Priess JR. A role for the centrosome and PAR-3 in the hand-off of MTOC function during epithelial polarization. Curr Biol 2012 22(7) 575-82  [ PubMed ID = 22425160 ] [ RRC reference ] Beatty A, Morton D, Kemphues K. The C. elegans homolog of Drosophila Lethal giant larvae functions redundantly with PAR-2 to maintain polarity in the early embryo. Development 2010 137(23) 3995-4004  [ PubMed ID = 21041363 ] [ RRC reference ] Achilleos A, Wehman AM, Nance J. PAR-3 mediates the initial clustering and apical localization of junction and polarity proteins during C. elegans intestinal epithelial cell polarization. Development 2010 137(11) 1833-42  [ PubMed ID = 20431121 ] [ RRC reference ]