分離済み変異体

tm2708

Allele Nametm2708
BalanceNot Required
OutCrossNot Accepted
Sequence NamePDB1.1
Gene NamePDB1.1
Worm BaseAllele Name tm2708
Gene Name PDB1.1
Sequence PDB1.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 2620/2621-3063/3064 (443 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(1708..1935, 2070..2267, 2678..2900, 2947..3292, 3789..3819))
Map position-1.6
Balancer
Map position of balancer
Sequence of primersExtRev:ATGCGCTCCTTGAAGCCCAC,IntRev:ACGGGACTTAGTTTGGGACT,ExtFwd:GGCCGATGGGGAAATGACTA,IntFwd:CCCTGTTTTTGGGCTCGACT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Dejima K, Imae R, Suehiro Y, Yoshida K, Mitani S.
An endomembrane zinc transporter negatively regulates systemic RNAi in Caenorhabditis elegans.
iScience 2023 26(6) 106930 
[ PubMed ID = 37305693 ] [ RRC reference ]

Earley BJ, Cubillas C, Warnhoff K, Ahmad R, Alcantar A, Lyon MD, Schneider DL, Kornfeld K.
Cadmium hijacks the high zinc response by binding and activating the HIZR-1 nuclear receptor.
Proc Natl Acad Sci U S A 2021 118(42)  
[ PubMed ID = 34649987 ] [ RRC reference ]