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分離済み変異体

Allele Name		tm2697
Allele Type		バランス済
Sequence Name		ZK1128.2
Gene Name		mett-10
Worm Base	Allele Name	tm2697
	Gene Name	mett-10
	Sequence	ZK1128.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. T. Schedl: in frame deletion. Strain is a ts sterile/Pvl. At 20 C, the strain is fertile with about 10% penetrance of the Pvl. At 25 C, the strain is 100% sterile, with close to 90% penetrance of the Pvl.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		4946/4947-5503/5504 (557 bp deletion)
Chromosome		III
Putative gene structure		join(4106..4306, 4377..4676, 4731..4996, 5047..5215, 5264..5767)
Map position		1.84
Balancer		hT2 bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primers		ExtFwd:CAACTGTGATCGGCCCGGAA,IntRev:GAATGATCGGGCCAGGAACT,ExtRev:GCACTAGTTGATGAAGGTGT,IntFwd:GCGATGCATAACCGGGTGGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Dorsett M, Westlund B, Schedl T. METT-10, a putative methyltransferase, inhibits germ cell proliferative fate in Caenorhabditis elegans. Genetics 2009 183(1) 233-47  [ PubMed ID = 19596901 ] [ RRC reference ] Dorsett M, Schedl T. A role for dynein in the inhibition of germ cell proliferative fate. Mol Cell Biol 2009 29(22) 6128-39  [ PubMed ID = 19752194 ] [ RRC reference ]