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分離済み変異体

Allele Name		tm2648
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F46G10.7
Gene Name		sir-2.2
Worm Base	Allele Name	tm2648
	Gene Name	sir-2.2
	Sequence	F46G10.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. C-S. Chen: normal sensitivity to Bacillus pore-forming toxin.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		21558/21559-21977/21978 (419 bp deletion)
Chromosome		X
Putative gene structure		join(21078..21204, 21254..21356, 21574..21714, 21758..21838, 22298..22412, 22459..22641, 22803..22916)
Map position		11.32
Balancer
Map position of balancer
Sequence of primers		ExtFwd:AACAGTGGACAAGCTGCTTG,IntRev:GATTGTCTGCCATTCCACAC,IntFwd:CTTGTCATCTCTGGAGCAGG,ExtRev:GCGTCCATACTCTCTTAGAT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Tataridas-Pallas N, Aman Y, Williams R, Chapman H, Cheng KJH, Gomez-Paredes C, Bates GP, Labbadia J. Mitochondrial clearance and increased HSF-1 activity are coupled to promote longevity in fasted Caenorhabditis elegans. iScience 2024 27(6) 109834  [ PubMed ID = 38784016 ] [ RRC reference ] Wirth M, Karaca S, Wenzel D, Ho L, Tishkoff D, Lombard DB, Verdin E, Urlaub H, Jedrusik-Bode M, Fischle W. Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases. Mitochondrion 2013 13(6) 705-20  [ PubMed ID = 23438705 ] [ RRC reference ]