分離済み変異体

tm2645

Allele Nametm2645
BalanceCompleted
OutCrossNot Accepted
Sequence NameT24H10.6
Gene Namedyrb-1
Worm BaseAllele Name tm2645 (x1)
Gene Name dyrb-1
Sequence T24H10.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. B.A. Bowerman: Dpy, Egl, Pvl, 85% Emb, Dr. M. Gotta: J Cell Biol 179, 15 (2007).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8769/8770-9523/9524 (754 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(9324..9532, 9767..9845))
Map position1.04
BalancermIn1 [e128 mIs14]
Map position of balancer
Sequence of primersIntFwd:CCAACGCAACGGAAGCTAAG,ExtFwd:GGCGTACGGTAGTACTATAC,IntRev:ACGAGCACTTCAGATGTAAG,ExtRev:CTATCGGATTCGATGGCGTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Murari E, Meadows D, Cuda N, Mangone M.
A comprehensive analysis of 3'UTRs in Caenorhabditis elegans.
Nucleic Acids Res 2024 52(13) 7523-7538 
[ PubMed ID = 38917330 ] [ RRC reference ]

Chen X, Wang K, Mufti FUD, Xu D, Zhu C, Huang X, Zeng C, Jin Q, Huang X, Yan YH, Dong MQ, Feng X, Shi Y, Kennedy S, Guang S.
Germ granule compartments coordinate specialized small RNA production.
Nat Commun 2024 15(1) 5799 
[ PubMed ID = 38987544 ] [ RRC reference ]

Weng Y, Murphy CT.
Male-specific behavioral and transcriptomic changes in aging C. elegans neurons.
iScience 2024 27(6) 109910 
[ PubMed ID = 38783998 ] [ RRC reference ]

Feldman JL, Priess JR.
A role for the centrosome and PAR-3 in the hand-off of MTOC function during epithelial polarization.
Curr Biol 2012 22(7) 575-82 
[ PubMed ID = 22425160 ] [ RRC reference ]

Couwenbergs C, Labbé JC, Goulding M, Marty T, Bowerman B, Gotta M.
Heterotrimeric G protein signaling functions with dynein to promote spindle positioning in C. elegans.
J Cell Biol 2007 179(1) 15-22 
[ PubMed ID = 17908918 ] [ RRC reference ]

O'Rourke SM, Dorfman MD, Carter JC, Bowerman B.
Dynein modifiers in C. elegans: light chains suppress conditional heavy chain mutants.
PLoS Genet 2007 3(8) e128 
[ PubMed ID = 17676955 ] [ RRC reference ]