分離済み変異体

tm2644

Allele Nametm2644
BalanceNot Required
OutCrossNot Accepted
Sequence NameF56A3.2
Gene Namegiyd-1
Worm BaseAllele Name tm2644
Gene Name giyd-1
Sequence F56A3.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 14117/14118-14322/14323 (205 bp deletion)
ChromosomeI
Putative gene structurejoin(11707..11819, 11865..12243, 13559..13737, 13798..13941, 14271..14346, 14404..14559, 14614..14805, 15019..15111)
Map position-0.31
Balancer
Map position of balancer
Sequence of primersExtFwd:AGCGTTTACTCCTCGCGGAA,IntFwd:CCGCAAGGATTATACAAGCT,ExtRev:GGGTAGTACACAATCTGCGT,IntRev:ACATGTTGGGCAATTGGCTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Rieckher M, Gallrein C, Alquezar-Artieda N, Bourached-Silva N, Vaddavalli PL, Mares D, Backhaus M, Blindauer T, Greger K, Wiesner E, Pontel LB, Schumacher B.
Distinct DNA repair mechanisms prevent formaldehyde toxicity during development, reproduction and aging.
Nucleic Acids Res 2024 52(14) 8271-8285 
[ PubMed ID = 38894680 ] [ RRC reference ]

Loose JA, Amrit FRG, Patil T, Yanowitz JL, Ghazi A.
Meiotic dysfunction accelerates somatic aging in Caenorhabditis elegans.
Aging Cell 2022 21(11) e13716 
[ PubMed ID = 36176234 ] [ RRC reference ]

Ujisawa T, Ohta A, Ii T, Minakuchi Y, Toyoda A, Ii M, Kuhara A.
Endoribonuclease ENDU-2 regulates multiple traits including cold tolerance via cell autonomous and nonautonomous controls in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2018 115(35) 8823-8828 
[ PubMed ID = 30104389 ] [ RRC reference ]

Saito TT, Colaiácovo MP.
Regulation of Crossover Frequency and Distribution during Meiotic Recombination.
Cold Spring Harb Symp Quant Biol 2017 82 223-234 
[ PubMed ID = 29222342 ] [ RRC reference ]

Wilson DM 3rd, Rieckher M, Williams AB, Schumacher B.
Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans.
Nucleic Acids Res 2017 45(16) 9467-9480 
[ PubMed ID = 28934497 ] [ RRC reference ]

Kessler Z, Yanowitz J.
Methodological considerations for mutagen exposure in C. elegans.
Methods 2014 68(3) 441-9 
[ PubMed ID = 24768858 ] [ RRC reference ]

Agostinho A, Meier B, Sonneville R, Jagut M, Woglar A, Blow J, Jantsch V, Gartner A.
Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases.
PLoS Genet 2013 9(7) e1003591 
[ PubMed ID = 23901331 ] [ RRC reference ]

Saito TT, Mohideen F, Meyer K, Harper JW, Colaiácovo MP.
SLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germline.
PLoS Genet 2012 8(8) e1002888 
[ PubMed ID = 22927825 ] [ RRC reference ]