分離済み変異体

tm2625

Allele Nametm2625
BalanceCompleted
OutCrossNot Accepted
Sequence NameY57A10A.19
Gene Namersr-2
Worm BaseAllele Name tm2625 (x1)
Gene Name rsr-2
Sequence Y57A10A.19
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 89380/89381-GT-89717/89718 (337 bp deletion + 2 bp insertion)
ChromosomeII
Putative gene structurejoin(88988..89077, 89226..90206, 90647..90853)
Map position7.09
BalancermnC1 [dpy-10(e128) unc52(e444) nIs190 let-?]
Map position of balancer
Sequence of primersIntFwd:CTCCTAGAGGACAAGGGCCT,ExtFwd:CGAGGTGAAATGCACCGAAT,ExtRev:ATCCCGGCGTTGTGGTGACT,IntRev:TTGTGGTGACTTCCGACGCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Fontrodona L, Porta-de-la-Riva M, Morán T, Niu W, Díaz M, Aristizábal-Corrales D, Villanueva A, Schwartz S Jr, Reinke V, Cerón J.
RSR-2, the Caenorhabditis elegans ortholog of human spliceosomal component SRm300/SRRM2, regulates development by influencing the transcriptional machinery.
PLoS Genet 2013 9(6) e1003543 
[ PubMed ID = 23754964 ] [ RRC reference ]