分離済み変異体

tm2613

Allele Nametm2613
BalanceNot Required
OutCrossNot Accepted
Sequence NameF53H8.4
Gene Namesms-2
Worm BaseAllele Name tm2613
Gene Name sms-2
Sequence F53H8.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 7943/7944-8225/8226 (282 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(7501..7633, 8034..8210, 8278..8427, 8905..9111, 9742..9965, 11000..11116))
Map position-18.92
Balancer
Map position of balancer
Sequence of primersIntRev:ATTAAAGTGCAGGGTGACCA,ExtFwd:CATTAACTTGGCCAGTGCAG,IntFwd:TGGCCAGTGCAGTTTACCAC,ExtRev:TCTGCTTACATTGGGCACAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Guzman G, Jahn H, Farley SE, Kyle JE, Bramer LM, Hoetzl S, van den Dikkenberg J, Hermansson M, Holthuis JCM, Tafesse FG.
Characterization of Caenorhabditis elegans sphingomyelin synthases through heterologous expression.
J Biol Chem 2025 301(7) 110300 
[ PubMed ID = 40473211 ] [ RRC reference ]

Hao L, Ben-David O, Babb SM, Futerman AH, Cohen BM, Buttner EA.
Clozapine Modulates Glucosylceramide, Clears Aggregated Proteins, and Enhances ATG8/LC3 in Caenorhabditis elegans.
Neuropsychopharmacology 2017 42(4) 951-962 
[ PubMed ID = 27711049 ] [ RRC reference ]