分離済み変異体

tm2557

Allele Nametm2557
BalanceNot Required
OutCrossNot Accepted
Sequence NameY38C1BA.2
Gene Namesnn-1
Worm BaseAllele Name tm2557
Gene Name snn-1
Sequence Y38C1BA.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. P. Juo: weak Hic.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 20204/20205-20454/20455 (250 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(18909..19126, 19200..19358, 19967..20237, 20349..20531, 21816..22229))
Map position-15.91
Balancer
Map position of balancer
Sequence of primersExtRev:CCCGATGGTTGTCTCAGTGA,IntRev:AACGAGGGATTCCAGGGAAT,ExtFwd:ATCACGGAGTTTCGCGCGTT,IntFwd:ACTCTCTCGTCACCCACCTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Stratigi A, Soler-García M, Krout M, Shukla S, De Bono M, Richmond JE, Laurent P.
Neuroendocrine Control of Synaptic Transmission by PHAC-1 in C. elegans.
J Neurosci 2025 45(13)  
[ PubMed ID = 39919830 ] [ RRC reference ]

Yu SC, Liewald JF, Shao J, Steuer Costa W, Gottschalk A.
Synapsin Is Required for Dense Core Vesicle Capture and cAMP-Dependent Neuropeptide Release.
J Neurosci 2021 41(19) 4187-4201 
[ PubMed ID = 33820857 ] [ RRC reference ]

Stavoe AK, Nelson JC, Martínez-Velázquez LA, Klein M, Samuel AD, Colón-Ramos DA.
Synaptic vesicle clustering requires a distinct MIG-10/Lamellipodin isoform and ABI-1 downstream from Netrin.
Genes Dev 2012 26(19) 2206-21 
[ PubMed ID = 23028145 ] [ RRC reference ]