分離済み変異体

tm2549

Allele Nametm2549
BalanceNot Required
OutCrossNot Accepted
Sequence NameC27A12.8
Gene Nameari-1
Worm BaseAllele Name tm2549
Gene Name ari-1
Sequence C27A12.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. W. Vermeulen: not sensitive to UV-irradiation.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 23395/23396-24218/24219 (823 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(22333..22431, 22508..22780, 22831..23271, 23317..23442, 23634..24026, 24070..24156, 24367..24432))
Map position0.71
Balancer
Map position of balancer
Sequence of primersExtFwd:CCTTCGGAACAATGGTCTAG,IntFwd:CGATGTTCTACGTATCGGTA,ExtRev:ATATGGACGACAGTGACTCA,IntRev:CGACAGTGACTCAAGTCAAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Poush JA, Blouin NA, Di Bona KR, Lažetić V, Fay DS.
Regulation of germ cell development by ARI1 family ubiquitin ligases in C. elegans.
Sci Rep 2018 8(1) 17737 
[ PubMed ID = 30531803 ] [ RRC reference ]

Polley SR, Kuzmanov A, Kuang J, Karpel J, Lažetić V, Karina EI, Veo BL, Fay DS.
Implicating SCF complexes in organogenesis in Caenorhabditis elegans.
Genetics 2014 196(1) 211-23 
[ PubMed ID = 24214340 ] [ RRC reference ]

Fay DS, Polley SR, Kuang J, Kuzmanov A, Hazel JW, Mani K, Veo BL, Yochem J.
A regulatory module controlling pharyngeal development and function in Caenorhabditis elegans.
Genetics 2012 191(3) 827-43 
[ PubMed ID = 22542967 ] [ RRC reference ]

Mani K, Fay DS.
A mechanistic basis for the coordinated regulation of pharyngeal morphogenesis in Caenorhabditis elegans by LIN-35/Rb and UBC-18-ARI-1.
PLoS Genet 2009 5(6) e1000510 
[ PubMed ID = 19521497 ] [ RRC reference ]