分離済み変異体

tm2535

Allele Nametm2535
BalanceNot Required
OutCrossNot Accepted
Sequence NameT09A12.2a
Gene NameT09A12.2
Worm BaseAllele Name tm2535
Gene Name T09A12.2
Sequence T09A12.2a
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. H. Sawa: not Psa. Dr. O. Blacque: WT Dyf phenotype.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8870/8871-C-9092/9093 (222 bp deletion + 1 bp insertion)
ChromosomeIV
Putative gene structurejoin(8353..8501, 8961..9189)
Map position3.68
Balancer
Map position of balancer
Sequence of primersExtFwd:CCGGCTGATCTCTTCTTCCA,ExtRev:CTGACCATTTACCTCGATCT,IntFwd:CTGCCTTTTAAGGCAACCGA,IntRev:AACCGTATGTGCCTTGATAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Schiavi A, Salveridou E, Brinkmann V, Shaik A, Menzel R, Kalyanasundaram S, Nygård S, Nilsen H, Ventura N.
Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players.
iScience 2023 26(4) 106448 
[ PubMed ID = 37020951 ] [ RRC reference ]

Tsai Y, Lin YC, Lee YH.
Octopamine-MAPK-SKN-1 signaling suppresses mating-induced oxidative stress in Caenorhabditis elegans gonads to protect fertility.
iScience 2023 26(3) 106162 
[ PubMed ID = 36876134 ] [ RRC reference ]

Han Y, Song S, Wu H, Zhang J, Ma E.
Antioxidant enzymes and their role in phoxim and carbaryl stress in Caenorhabditis elegans.
Pestic Biochem Physiol 2017 138 43-50 
[ PubMed ID = 28456303 ] [ RRC reference ]

Sakamoto T, Maebayashi K, Nakagawa Y, Imai H.
Deletion of the four phospholipid hydroperoxide glutathione peroxidase genes accelerates aging in Caenorhabditis elegans.
Genes Cells 2014 19(10) 778-92 
[ PubMed ID = 25200408 ] [ RRC reference ]

Song S, Zhang X, Wu H, Han Y, Zhang J, Ma E, Guo Y.
Molecular basis for antioxidant enzymes in mediating copper detoxification in the nematode Caenorhabditis elegans.
PLoS One 2014 9(9) e107685 
[ PubMed ID = 25243607 ] [ RRC reference ]

Erkut C, Vasilj A, Boland S, Habermann B, Shevchenko A, Kurzchalia TV.
Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation.
PLoS One 2013 8(12) e82473 
[ PubMed ID = 24324795 ] [ RRC reference ]