分離済み変異体

tm2530

Allele Nametm2530
BalanceNot Required
OutCrossNot Accepted
Sequence NameY51H1A.4
Gene Nameing-3
Worm BaseAllele Name tm2530
Gene Name ing-3
Sequence Y51H1A.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 21827/21828-22792/22793 (965 bp deletion)
ChromosomeII
Putative gene structurejoin(19135..19162, 19229..19300, 19354..19457, 20843..21367, 22500..23114, 25209..25337)
Map position20.7
Balancer
Map position of balancer
Sequence of primersIntRev:GCCCACACTAACATGACGAT,ExtRev:TCGCACTATTTCTGCTGGGA,IntFwd:GCGTGCTAGCTCAACGCAAA,ExtFwd:CTCCACAATCCGCGTGCTAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Kendler J, Wӧls F, Thapliyal S, Arcalis E, Gabriel H, Kubitschek S, Malzl D, Strobl MR, Palmberger D, Luber T, Unverzagt C, Paschinger K, Glauser DA, Wilson IBH, Yan S.
N-glycan core tri-fucosylation requires Golgi α-mannosidase III activity that impacts nematode growth and behavior.
J Biol Chem 2024 300(12) 107944 
[ PubMed ID = 39481603 ] [ RRC reference ]

Mariani L, Lussi YC, Vandamme J, Riveiro A, Salcini AE.
The H3K4me3/2 histone demethylase RBR-2 controls axon guidance by repressing the actin-remodeling gene wsp-1.
Development 2016 143(5) 851-63 
[ PubMed ID = 26811384 ] [ RRC reference ]

Wohlschlager T, Butschi A, Grassi P, Sutov G, Gauss R, Hauck D, Schmieder SS, Knobel M, Titz A, Dell A, Haslam SM, Hengartner MO, Aebi M, Künzler M.
Methylated glycans as conserved targets of animal and fungal innate defense.
Proc Natl Acad Sci U S A 2014 111(27) E2787-96 
[ PubMed ID = 24879441 ] [ RRC reference ]

Luo J, Shah S, Riabowol K, Mains PE.
The Caenorhabditis elegans ing-3 gene regulates ionizing radiation-induced germ-cell apoptosis in a p53-associated pathway.
Genetics 2009 181(2) 473-82 
[ PubMed ID = 19015549 ] [ RRC reference ]