分離済み変異体

tm2528

Allele Nametm2528
BalanceNot Required
OutCrossNot Accepted
Sequence NameY38F2AR.1
Gene Nameeri-5
Worm BaseAllele Name tm2528
Gene Name eri-5
Sequence Y38F2AR.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 58824/58825-59191/59192 (367 bp deletion)
ChromosomeIV
Putative gene structurejoin(58785..59213, 59986..60223, 61029..61322, 61514..61625, 63061..63398, 63818..64002)
Map position-7.53
Balancer
Map position of balancer
Sequence of primersExtRev:ACAACATGCGATCGGCGGGA,IntRev:GACCGAAAGGTGCACCAAAC,ExtFwd:CCTCAAGACCAGGTGCTGCA,IntFwd:TAGAGCGCGTTTGAGGCATG
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Almeida MV, Dietz S, Redl S, Karaulanov E, Hildebrandt A, Renz C, Ulrich HD, König J, Butter F, Ketting RF.
GTSF-1 is required for formation of a functional RNA-dependent RNA Polymerase complex in Caenorhabditis elegans.
EMBO J 2018 37(12)  
[ PubMed ID = 29769402 ] [ RRC reference ]

Thivierge C, Makil N, Flamand M, Vasale JJ, Mello CC, Wohlschlegel J, Conte D Jr, Duchaine TF.
Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi.
Nat Struct Mol Biol 2011 19(1) 90-7 
[ PubMed ID = 22179787 ] [ RRC reference ]