Home > 分離済み変異体 > tm2525

分離済み変異体

Allele Name		tm2525
Balance		Not Required
OutCross		Not Accepted
Sequence Name		R153.1
Gene Name		pde-4
Worm Base	Allele Name	tm2525
	Gene Name	pde-4
	Sequence	R153.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. A. Chisholm: normal touch neuron morphology.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		4129/4130-4457/4458 (328 bp deletion)
Chromosome		II
Putative gene structure		complement(join(2351..3347, 3459..3641, 3694..3816, 4035..4189, 4598..4697, 4749..5171, 5990..6130, 7365..7441, 7859..7961, 8812..8905, 9265..9452))
Map position		0.51
Balancer
Map position of balancer
Sequence of primers		ExtFwd:TGTACCCACACGTGATCAAC,IntFwd:CCGGTCCTTCATCTCTTTAT,ExtRev:GGTACAAGGCCCTTCTACAT,IntRev:AGCTCAAACAGCAGCCATGA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Schiavi A, Salveridou E, Brinkmann V, Shaik A, Menzel R, Kalyanasundaram S, Nygård S, Nilsen H, Ventura N. Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players. iScience 2023 26(4) 106448  [ PubMed ID = 37020951 ] [ RRC reference ] Sakamoto T, Maebayashi K, Tsunoda Y, Imai H. Inhibition of lipid peroxidation during the reproductive period extends the lifespan of Caenorhabditis elegans. J Clin Biochem Nutr 2020 66(2) 116-123  [ PubMed ID = 32231407 ] [ RRC reference ] Sakamoto T, Maebayashi K, Nakagawa Y, Imai H. Deletion of the four phospholipid hydroperoxide glutathione peroxidase genes accelerates aging in Caenorhabditis elegans. Genes Cells 2014 19(10) 778-92  [ PubMed ID = 25200408 ] [ RRC reference ]