分離済み変異体

tm2518

Allele Nametm2518
BalanceNot Required
OutCrossNot Accepted
Sequence NameF54C9.11
Gene NameF54C9.11
Worm BaseAllele Name tm2518
Gene Name F54C9.11
Sequence F54C9.11
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. O. Blacque: dye-filling normal.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 29794/29795-30365/30366 (571 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(29376..30086, 30266..30470, 30855..30925))
Map position0.82
Balancer
Map position of balancer
Sequence of primersExtRev:GATCCGATGCCCCATTCGTT,IntRev:TCCCCTTCGTTACATCACCA,ExtFwd:AGTCACAGACTGCGGCAATC,IntFwd:GCGCGCACCTTTTTGGCAGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Sun Y, Zhang M, Ge L.
A RAB transition orchestrates membrane trafficking in unconventional protein secretion.
J Cell Biol 2024 223(2)  
[ PubMed ID = 38180797 ] [ RRC reference ]

Li X, Liu B, Wen Y, Wang J, Guo YR, Shi A, Lin L.
Coordination of RAB-8 and RAB-11 during unconventional protein secretion.
J Cell Biol 2024 223(2)  
[ PubMed ID = 38019180 ] [ RRC reference ]

Wang X, Li X, Wang J, Wang J, Hu C, Zeng J, Shi A, Lin L.
SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion.
J Cell Biol 2022 221(7)  
[ PubMed ID = 35604368 ] [ RRC reference ]

Choi J, Sung JY, Lee S, Yoo J, Rongo C, Kim YN, Shim J.
Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling.
Int J Mol Sci 2020 21(20)  
[ PubMed ID = 33092268 ] [ RRC reference ]