分離済み変異体

tm2497

Allele Nametm2497
BalanceNot Required
OutCrossNot Accepted
Sequence NameR166.1
Gene Namemab-10
Worm BaseAllele Name tm2497
Gene Name mab-10
Sequence R166.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. R.H. Horvitz: Pvl and often rupture from their vulva.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 4036/4037-4461/4462 (425 bp deletion)
ChromosomeII
Putative gene structurejoin(3473..3566, 3617..4012, 4374..4799, 5206..5341, 5390..5777, 6142..6210)
Map position2.65
Balancer
Map position of balancer
Sequence of primersExtFwd:ATCAACCAGCAATGCAGATC,ExtRev:TCGGTGAGTTGAGGTTAGTG,IntFwd:CAGCAATGCAGATCGCCCTG,IntRev:TCTTGGCCGGTGATGGACGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Doi A, Suarez GD, Droste R, Horvitz HR.
A DEAD-box helicase drives the partitioning of a pro-differentiation NAB protein into nuclear foci.
Nat Commun 2023 14(1) 6593 
[ PubMed ID = 37852948 ] [ RRC reference ]

Harris DT, Horvitz HR.
MAB-10/NAB acts with LIN-29/EGR to regulate terminal differentiation and the transition from larva to adult in C. elegans.
Development 2011 138(18) 4051-62 
[ PubMed ID = 21862562 ] [ RRC reference ]