分離済み変異体

tm2486

Allele Nametm2486
Allele Type通常株
Sequence NameY47H9C.6
Gene Namecsp-3
Worm BaseAllele Name tm2486
Gene Name csp-3
Sequence Y47H9C.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 58027/58028-58740/58741 (713 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(58017..58073, 58116..58352, 58397..58522))
Map position12.87
Balancer
Map position of balancer
Sequence of primersExtRev:CGCCTCAAACGCCACTGGAT,IntRev:CGCCACTGGATTCTCTGGTA,IntFwd:ATTCATCGTAGCAGCGGGAA,ExtFwd:GCTAGCATGACATCGTCACA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Jeong PY, Kumar A, Joshi PM, Rothman JH.
Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death.
Sci Rep 2020 10(1) 6159 
[ PubMed ID = 32273538 ] [ RRC reference ]

Huang CY, Chen JY, Wu SC, Tan CH, Tzeng RY, Lu PJ, Wu YF, Chen RH, Wu YC.
C. elegans EIF-3.K promotes programmed cell death through CED-3 caspase.
PLoS One 2012 7(5) e36584 
[ PubMed ID = 22590572 ] [ RRC reference ]

Geng X, Shi Y, Nakagawa A, Yoshina S, Mitani S, Shi Y, Xue D.
Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3.
Nat Struct Mol Biol 2008 15(10) 1094-101 
[ PubMed ID = 18776901 ] [ RRC reference ]