Home > 分離済み変異体 > tm2467

分離済み変異体

Allele Name		tm2467
Allele Type		通常株
Sequence Name		Y51H4A.12
Gene Name		set-26
Worm Base	Allele Name	tm2467
	Gene Name	set-26
	Sequence	Y51H4A.12
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		178788/178789-179878/179875 (1090 bp deletion)
Chromosome		IV
Putative gene structure		complement(join(175289..175332, 175464..175728, 176384..177177, 177711..177984, 178467..180302, 181241..182147, 183042..183382, 183470..183840, 183892..183997))
Map position		15.14
Balancer
Map position of balancer
Sequence of primers		ExtFwd:AAGACGAGACCCTGGCAATG,IntFwd:TCGAATCGAAACCACGCCAG,ExtRev:CCGCCGAACTTCCTCCTCAA,IntRev:AAGCCTCCGACGCTCCTCAT
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Emerson FJ, Chiu C, Lin LY, Riedel CG, Zhu M, Lee SS. The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans. bioRxiv 2023    [ PubMed ID = 36993207 ] [ RRC reference ] Bazopoulou D, Knoefler D, Zheng Y, Ulrich K, Oleson BJ, Xie L, Kim M, Kaufmann A, Lee YT, Dou Y, Chen Y, Quan S, Jakob U. Developmental ROS individualizes organismal stress resistance and lifespan. Nature 2019 576(7786) 301-305  [ PubMed ID = 31801997 ] [ RRC reference ] Wang W, Chaturbedi A, Wang M, An S, Santhi Velayudhan S, Lee SS. SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity. Elife 2018 7   [ PubMed ID = 29714684 ] [ RRC reference ] Hajduskova M, Baytek G, Kolundzic E, Gosdschan A, Kazmierczak M, Ofenbauer A, Beato Del Rosal ML, Herzog S, Ul Fatima N, Mertins P, Seelk-Müthel S, Tursun B. MRG-1/MRG15 Is a Barrier for Germ Cell to Neuron Reprogramming in Caenorhabditis elegans. Genetics 2019 211(1) 121-139  [ PubMed ID = 30425042 ] [ RRC reference ] Erdelyi P, Wang X, Suleski M, Wicky C. A Network of Chromatin Factors Is Regulating the Transition to Postembryonic Development in Caenorhabditis elegans. G3 (Bethesda) 2017 7(2) 343-353  [ PubMed ID = 28007841 ] [ RRC reference ] Ni Z, Ebata A, Alipanahiramandi E, Lee SS. Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegans. Aging Cell 2012 11(2) 315-25  [ PubMed ID = 22212395 ] [ RRC reference ]