分離済み変異体

tm2447

Allele Nametm2447
BalanceNot Required
OutCrossNot Accepted
Sequence NameM142.6
Gene Namerle-1
Worm BaseAllele Name tm2447
Gene Name rle-1
Sequence M142.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. P. Hu: normal lifespan at 25C, does not enhance akt-1 dauer arrest.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 35792/35793-36054/36055 (262 bp deletion)
ChromosomeIII
Putative gene structurejoin(34039..34101, 34448..34750, 35530..36306, Z99276.1:105..698, Z99276.1:1364..1566, Z99276.1:1666..1772, Z99276.1:2495..2795, Z99276.1:3714..3928, Z99276.1:4056..4104, Z99276.1:5846..5958, Z99276.1:6478..6729, Z99276.1:7169..7338)
Map position5.65
Balancer
Map position of balancer
Sequence of primersIntFwd:TCGCGGACCCTCCAACGAAA,ExtFwd:CAGGAAATCTCGCGGACCCT,IntRev:CGCATCGAGGTATCCTCATG,ExtRev:GGTGCAATGCATCTCCGATC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Alam H, Williams TW, Dumas KJ, Guo C, Yoshina S, Mitani S, Hu PJ.
EAK-7 controls development and life span by regulating nuclear DAF-16/FoxO activity.
Cell Metab 2010 12(1) 30-41 
[ PubMed ID = 20620993 ] [ RRC reference ]