Home > 分離済み変異体 > tm2435

分離済み変異体

Allele Name		tm2435
Balance		Not Required
OutCross		Not Accepted
Sequence Name		R119.7
Gene Name		rnp-8
Worm Base	Allele Name	tm2435
	Gene Name	rnp-8
	Sequence	R119.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. J. Kimble: low percentage sterility.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		7405/7046-CTTTTTTTT-8031/8032 (626 bp deletion + 9 bp insertion)
Chromosome		I
Putative gene structure		join(7315..7475, 7532..7987, 8327..8392, 8440..8756, 9449..10005, 10542..10736)
Map position		-19.06
Balancer
Map position of balancer
Sequence of primers		ExtFwd:GATGAATGGTCAAGCGGATC,ExtRev:GCATAAACAACTGGCGACGA,IntFwd:GAACCGCCTACGTTTCGGGT,IntRev:GGCGACGATGTTCTCGGGTA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Tsukamoto T, Gearhart MD, Spike CA, Huelgas-Morales G, Mews M, Boag PR, Beilharz TH, Greenstein D. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Genetics 2017 206(4) 2007-2039  [ PubMed ID = 28576864 ] [ RRC reference ] Zanetti S, Puoti A. Sex determination in the Caenorhabditis elegans germline. Adv Exp Med Biol 2013 757 41-69  [ PubMed ID = 22872474 ] [ RRC reference ] Zanetti S, Grinschgl S, Meola M, Belfiore M, Rey S, Bianchi P, Puoti A. The sperm-oocyte switch in the C. elegans hermaphrodite is controlled through steady-state levels of the fem-3 mRNA. RNA 2012 18(7) 1385-94  [ PubMed ID = 22635404 ] [ RRC reference ] Kim KW, Wilson TL, Kimble J. GLD-2/RNP-8 cytoplasmic poly(A) polymerase is a broad-spectrum regulator of the oogenesis program. Proc Natl Acad Sci U S A 2010 107(40) 17445-50  [ PubMed ID = 20855596 ] [ RRC reference ] Kim KW, Nykamp K, Suh N, Bachorik JL, Wang L, Kimble J. Antagonism between GLD-2 binding partners controls gamete sex. Dev Cell 2009 16(5) 723-33  [ PubMed ID = 19460348 ] [ RRC reference ]