Home > 分離済み変異体 > tm2421

分離済み変異体

Allele Name		tm2421
Balance		Completed
OutCross		Not Accepted
Sequence Name		B0240.2
Gene Name		spe-42
Worm Base	Allele Name	tm2421 (x1)
	Gene Name	spe-42
	Sequence	B0240.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. S. L'Hernault: Ste because of sperm defect
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		18332/18333-18992/18993 (660 bp deletion)
Chromosome		V
Putative gene structure		complement(join(16923..17011, 17055..17206, 17643..17764, 17812..18072, 18139..18176, 18294..18450, 18507..18914, 18959..19148, 19221..19438, 19629..19692, 19740..19844, 19896..20027, 20073..20158))
Map position		3.34
Balancer		nT1 [qIs51]
Map position of balancer
Sequence of primers		IntRev:CTGGTCCAATGAATAAGGTC,ExtRev:CAGGGTCCTGCAATGAATGT,IntFwd:AGGCTCAATGCACGAATTCT,ExtFwd:CAGTCAACTCGAGACCGGAA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Takayama J, Tajima T, Onami S, Nishimura H. C. elegans spermatozoa lacking spe-45 are incapable of fusing with the oocyte plasma membrane. MicroPubl Biol 2021 2021   [ PubMed ID = 33644705 ] [ RRC reference ] Nishimura H, Tajima T, Comstra HS, Gleason EJ, L'Hernault SW. The Immunoglobulin-like Gene spe-45 Acts during Fertilization in Caenorhabditis elegans like the Mouse Izumo1 Gene. Curr Biol 2015 25(24) 3225-31  [ PubMed ID = 26671669 ] [ RRC reference ] Wilson LD, Sackett JM, Mieczkowski BD, Richie AL, Thoemke K, Rumbley JN, Kroft TL. Fertilization in C. elegans requires an intact C-terminal RING finger in sperm protein SPE-42. BMC Dev Biol 2011 11 10  [ PubMed ID = 21345212 ] [ RRC reference ]