分離済み変異体

tm2418

Allele Nametm2418
Allele Type通常株
Sequence NameT05F1.10
Gene Namedhs-4
Worm BaseAllele Name tm2418
Gene Name dhs-4
Sequence T05F1.10
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. I. Mori: weakly abnormal thermotaxis when culture at 17˚C.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 28311/28312-TTT-28755/28756 (444 bp deletion + 3 bp insertion)
ChromosomeI
Putative gene structurecomplement(join(27516..27594, 27639..27764, 28054..28208, 28314..28409, 28455..28528, 28578..28695, 28746..29015))
Map position3.83
Balancer
Map position of balancer
Sequence of primersIntRev:GGGGTATTCTCATTGTGGTC,IntFwd:TAGCTGCTCCAGTGGCGTCA,ExtFwd:GAAGGCATACCTGGTAGCTG,ExtRev:AACACGCAGCAGTTGGATTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Okahata M, Wei AD, Ohta A, Kuhara A.
Cold acclimation via the KQT-2 potassium channel is modulated by oxygen in Caenorhabditis elegans.
Sci Adv 2019 5(2) eaav3631 
[ PubMed ID = 30775442 ] [ RRC reference ]

Sugi T, Nishida Y, Mori I.
Regulation of behavioral plasticity by systemic temperature signaling in Caenorhabditis elegans.
Nat Neurosci 2011 14(8) 984-92 
[ PubMed ID = 21706021 ] [ RRC reference ]

Ohta A, Ujisawa T, Sonoda S, Kuhara A.
Light and pheromone-sensing neurons regulates cold habituation through insulin signalling in Caenorhabditis elegans.
Nat Commun 2014 5 4412 
[ PubMed ID = 25048458 ] [ RRC reference ]