分離済み変異体

tm2404

Allele Nametm2404
BalanceNot Required
OutCrossNot Accepted
Sequence NameY116A8C.26
Gene Namesnx-13
Worm BaseAllele Name tm2404
Gene Name snx-13
Sequence Y116A8C.26
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. Z. Zhou: no persistent cell corpses.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 186825/186826-CCAAAAA-187102/187103 (277 bp deletion + 7 bp insertion)
ChromosomeIV
Putative gene structurecomplement(join(179756..179917, 179972..180125, 180489..180697, 180743..180820, 181317..181667, 182508..182747, 183552..183755, 183957..184082, 185143..185600, 186245..186343, 186395..186636, 186713..186834, 186883..187084, 187131..187237))
Map position16.13
Balancer
Map position of balancer
Sequence of primersExtRev:ACGTTCCCTTGTCCCCGAGA,IntRev:ACATTCGGTTCAACCGGTCT,ExtFwd:GAGTATACTCGTGGCTCGCA,IntFwd:CTCGTGGCTCGCAAATCTAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Tian Y, Kang Q, Shi X, Wang Y, Zhang N, Ye H, Xu Q, Xu T, Zhang R.
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
PLoS Genet 2021 17(6) e1009607 
[ PubMed ID = 34081703 ] [ RRC reference ]

Vieira N, Bessa C, Rodrigues AJ, Marques P, Chan FY, de Carvalho AX, Correia-Neves M, Sousa N.
Sorting nexin 3 mutation impairs development and neuronal function in Caenorhabditis elegans.
Cell Mol Life Sci 2018 75(11) 2027-2044 
[ PubMed ID = 29196797 ] [ RRC reference ]

Lu N, Shen Q, Mahoney TR, Liu X, Zhou Z.
Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling.
Mol Biol Cell 2011 22(3) 354-74 
[ PubMed ID = 21148288 ] [ RRC reference ]