分離済み変異体

tm2395

Allele Nametm2395
BalanceRequest Available
OutCrossNot Accepted
Sequence NameC07A9.3
Gene Nametlk-1
Worm BaseAllele Name tm2395 (x1)
Gene Name tlk-1
Sequence C07A9.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr.J.M. Schumacher: Ste.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 44263/44264-44941/44942 (678 bp deletion)
ChromosomeIII
Putative gene structurejoin(34657..34941, 35031..35224, 35545..35555, 36082..36235, 36955..37007, 37134..37375, 42123..42227, 42870..43190, 43241..43464, 43974..44454, 44514..45944, 45995..46105, 46571..46654)
Map position0.91
Balancer
Map position of balancer
Sequence of primersExtFwd:GTCGACAGCCACTGACAAGA,IntFwd:GCGACGAAAAGCTGGTCCAA,ExtRev:GTACTGCAGGCATCTTCTTA,IntRev:GCGGAGCTCACCTAAAACAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Yang X, Wei R, Meng F, Liu D, Gong X, Ruvkun G, Wei W.
Mitochondrial fission surveillance is coupled to Caenorhabditis elegans DNA and chromosome segregation integrity.
PLoS Genet 2025 21(4) e1011678 
[ PubMed ID = 40279356 ] [ RRC reference ]

Yeh CH, Yang HJ, Lee IJ, Wu YC.
Caenorhabditis elegans TLK-1 controls cytokinesis by localizing AIR-2/Aurora B to midzone microtubules.
Biochem Biophys Res Commun 2010 400(2) 187-93 
[ PubMed ID = 20705056 ] [ RRC reference ]