Allele Name | tm2371 |
Allele Type | 通常株 |
Sequence Name | C34D4.14 |
Gene Name | hecd-1 |
Worm Base | Allele Name |
tm2371
|
Gene Name |
hecd-1
|
Sequence |
C34D4.14
|
Phenotype
Information from the receiver is posted in the form of a "researcher : phenotype"
| homozygous viable. Dr. A. Dernburg: No defects in growth, fertility or meiotic chromosome behavior. |
Mutation site
Please see gene structure to locate the deletion in relation to exon(s)
| 25747/25748-26737/26738 (990 bp deletion) |
Chromosome | IV |
Putative gene structure | complement(join(20024..20131, 20187..20260, 20307..20574, 20629..20773, 20820..21242, 21300..21730, 21780..22723, 22806..23669, 23851..24187, 24255..24422, 24478..25920, 25968..26228, 26279..26392, 26508..26645, 26823..27206, 27285..27943, 27989..28179, 28238..28476, 28522..29013, 29083..29327, 29374..29731)) |
Map position | 3.29 |
Balancer | |
Map position of balancer | |
Sequence of primers | IntFwd:TACCGAATGGTTGGCGAGTA,ExtFwd:TCTTCCATATCCACGCGAGT,IntRev:GCCAGGGAACACCTTATCGT,ExtRev:GACAGTATTGAGCCAGGGAA |
Distributed lab | |
Depositor | Dr. S. Mitani/NBRP |
References |
Please submit your publication
Segref A, Vakkayil KL, Padvitski T, Li Q, Kroef V, Lormann J, Körner L, Finger F, Hoppe T. Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling. Nat Commun 2022 13(1) 5874
[ PubMed ID = 36198694 ]
[ RRC reference ]
|
Ravanelli S, Li Q, Annibal A, Trifunovic A, Antebi A, Hoppe T. Reprograming of proteasomal degradation by branched chain amino acid metabolism. Aging Cell 2022 21(12) e13725
[ PubMed ID = 36168305 ]
[ RRC reference ]
|
Ackermann L, Schell M, Pokrzywa W, Kevei É, Gartner A, Schumacher B, Hoppe T. E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis. Nat Struct Mol Biol 2016 23(11) 995-1002
[ PubMed ID = 27669035 ]
[ RRC reference ]
|
Segref A, Kevei É, Pokrzywa W, Schmeisser K, Mansfeld J, Livnat-Levanon N, Ensenauer R, Glickman MH, Ristow M, Hoppe T. Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system. Cell Metab 2014 19(4) 642-52
[ PubMed ID = 24703696 ]
[ RRC reference ]
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