分離済み変異体

tm2359

Allele Nametm2359
BalanceNot Required
OutCrossNot Accepted
Sequence NameY48C3A.17
Gene Nameefl-2
Worm BaseAllele Name tm2359
Gene Name efl-2
Sequence Y48C3A.17
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. J. Kaplan: non-Egl, non-Unc.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 150519/150520-TTTCCAAATTTTTGGATGTNNCGNCCCCTTTGNGAAAATTTTTCTTT-150849/150850 (330 bp deletion + 47 bp insertion)
ChromosomeII
Putative gene structurejoin(150626..150918, 152479..152628, 153489..153582, 153776..154058, 154574..154735, 155490..155746)
Map position16.82
Balancer
Map position of balancer
Sequence of primersIntFwd:GCGTGGCTTATTGCACACTG,ExtFwd:ATGGGCGTGGCTTATTGCAC,IntRev:CTCCACATAACCGAGCCCCT,ExtRev:ATCGCACTAACATCCATCGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Chen J, Chitrakar R, Baugh LR.
DAF-18/PTEN protects LIN-35/Rb from CLP-1/CAPN-mediated cleavage to promote starvation resistance.
Life Sci Alliance 2025 8(6)  
[ PubMed ID = 40199585 ] [ RRC reference ]

Cao W, Fan Q, Amparado G, Begic D, Godini R, Gopal S, Pocock R.
A nucleic acid binding protein map of germline regulation in Caenorhabditis elegans.
Nat Commun 2024 15(1) 6884 
[ PubMed ID = 39128930 ] [ RRC reference ]

Schertel C, Conradt B.
C. elegans orthologs of components of the RB tumor suppressor complex have distinct pro-apoptotic functions.
Development 2007 134(20) 3691-701 
[ PubMed ID = 17881492 ] [ RRC reference ]